What are the Side Effects of Hydrocodone?

Article Details
  • Written By: Amanda Livingstone
  • Edited By: Jessica Seminara
  • Last Modified Date: 24 November 2018
  • Copyright Protected:
    Conjecture Corporation
  • Print this Article
Free Widgets for your Site/Blog
Pizza is one of the most universally addictive foods, due to its irresistible combination of fat, sugar, and salt.  more...

December 14 ,  1911 :  The first explorers reached the South Pole.  more...

Hydrocodone can produce many side effects that differ in severity, depending on the individual and the dosage. Common side effects include drowsiness, gastrointestinal issues, and blurred vision. More serious side effects include jaundice, organ failure, and severe allergic reaction.

A narcotic analgesic and cough suppressant, hydrocodone is generally prescribed to relieve moderate to severe pain. It comes in tablet, capsule, syrup, and solution forms. Like other narcotics, hydrocodone has the potential to become addictive and is sometimes misused as a euphoriant. Those taking this medication should avoid the use of alcohol, cocaine, amphetamines, barbiturates, benzodiazepines, and methylphenidates. Severe adverse reactions such as respiratory distress, organ failure, coma, and even death can occur when mixing hydrocodone with the aforementioned contraindicated agents.

Even with normal use, the side effects of hydrocodone may appear across multiple bodily systems, and can range from mild to severe. Drowsiness and decreased alertness are some of the most common side effects. For this reason, those taking hydrocodone should use caution when driving or working with heavy machinery. Blurred vision, another common side effect, can also become a dangerous problem while driving or operating machinery. Other typical reactions can include thickening of mucus in the nose or throat.


Hydrocodone can also affect the nervous system, causing dizziness, lightheadedness, stupor, agitation and euphoria. Stupor is a more severe form of drowsiness, wherein the sufferer usually lacks cognitive awareness and is generally unresponsive except to applied stimuli. Like most opiates, hydrocodone will often cause an exaggerated state of well-being better known as euphoria.

Gastrointestinal side effects of hydrocodone use include nausea, constipation, dry mouth and vomiting. In some people, vomiting can be severe enough to require hospitalization. When hydrocodone is prepared with acetaminophen, effects can become more severe for some patients, especially those who abuse alcohol or have preexisting liver or kidney conditions.

Acute pancreatitis is one of the rarer and less common side effects experienced by those consuming hydrocodone with acetaminophen. Alcoholic patients tend to experience greater levels of pancreatitis as well as hepatotoxicity leading to liver failure. Individuals with underlying kidney or liver conditions sometimes develop a kidney disorder called acute tubular necrosis from hydrocodone-acetaminophen related hepatotoxicity.

Other rare side effects of hydrocodone include erythematous skin rashes and severe allergic reactions. Patients experiencing allergic reactions may display symptoms such as hives, difficulty breathing, and swelling of the throat structures. Though rare, this type of severe allergic reaction often requires emergency medical care.


You might also Like


Discuss this Article

Post 3

@burcinc-- I think nightmares and vivid dreams are a rare side effect that happens at higher doses. Are you taking a high dose?

I don't take mine at night but I'm sure I would get nightmares too if I did. I was prescribed hydrocodone two months ago for my chronic hip pain. I only take it if I absolutely need it because it turns me into a zombie. I feel so out of it on this medication, I become extremely tired and I stop interacting with people.

Post 2

@ZipLine-- Do you experience vivid dreams and nightmares from hydrocodone?

I take my dose before bed time too because it makes me drowsy. But I've noticed that since I started taking it, I've been having a lot of nightmares and vivid dreams. I've never heard of this side effect of hydrocodone though so I'm wondering if I'm the only one who has it.

Post 1

The only hydrocodone side effect I experience is sleepiness. That's why I always take it before bed time because it puts me to sleep immediately.

Post your comments

Post Anonymously


forgot password?