What Are the Most Common Glucosamine Chondroitin Side Effects?

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  • Written By: Meshell Powell
  • Edited By: Melissa Wiley
  • Last Modified Date: 22 July 2019
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Glucosamine chondroitin side effects are relatively rare and are usually mild when they do occur, although any negative symptoms that begin after taking this medication should be reported to a doctor for further medical evaluation. Some of the most frequently reported glucosamine chondroitin side effects include gastrointestinal disturbances, dizziness, and headaches. Diabetic patients may experience an elevation of blood sugar levels when using this supplement. Some of the more serious potential side effects include heart palpitations, swelling, or respiratory distress. Any specific questions or concerns about potential glucosamine chondroitin side effects in an individual situation should be discussed with a doctor or other medical professional.

Gastrointestinal disturbances are among the most commonly reported glucosamine chondroitin side effects. Mild to moderate nausea may occur, with or without vomiting. Taking this medication with food or milk may help to lessen the severity of this symptom. Some people who take this nutritional supplement may experience diarrhea, constipation, or alternating bouts of both. Heartburn, bloating, and increased flatulence have also been reported by those taking this medication.

Headache, dizziness, and drowsiness are possible glucosamine chondroitin side effects. High blood sugar levels, known as hyperglycemia, may sometimes occur in patients who have diabetes. Those with respiratory conditions, such as asthma, may notice an increase in symptoms when taking this medication. While most of these side effects are usually mild, any persistent or bothersome symptoms should be discussed with a doctor.


More serious glucosamine chondroitin side effects that should be reported to a doctor immediately include chest pain, difficulty breathing, or significant hair loss. Swelling of the hands and feet should be reported right away as well, as this could be a sign of reduced kidney function. Facial swelling, especially if accompanied by breathing problems or difficulty swallowing, may indicate the presence of a potentially life-threatening allergic reaction known as anaphylaxis. Abdominal pain that mimics that of acid reflux should be evaluated to make sure that serious digestive complications are not present.

Some people may not be able to safely use glucosamine chondroitin supplements. If these patients decide to use this supplement, close medical monitoring is recommended. Those who are taking medications such as blood thinners or have a history of bleeding disorders should use extreme caution when using this supplement. Patients who have an allergy to shellfish should avoid the use of this product, as it is typically made with the shells of these sea creatures. Pregnant women and those who are breastfeeding are normally advised to avoid this medication.


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Post 3

The most serious side effect of glucoamine chondroitin is allergies. And it is possible, especially for people with a shellfish allergy because some glucosamine supplements are made from shellfish.

I've also heard that some glucosamine supplements are contaminated. So it's important to buy from a trustworthy manufacturer and also read the ingredients list carefully.

Post 2

SteamLouis-- Actually, glucosamine may or may not increase blood sugar. There really isn't a consensus on it. Earlier, doctors used to say that it did increase blood sugar. But there was a recent study that claimed the opposite.

My doctor told me to try it and check my blood sugar. I have been using it for a few days now and check my blood sugar several times a day. I haven't noticed an increase in my readings so far. But I will continue checking this week to make sure.

I suggest the same to other diabetics. Check with your doctor and if he or she approves, try a low dose while monitoring your blood sugar. If you see

an increase, don't take it. It's definitely a risk. For those who don't experience this side effect though, the advantages are more than the disadvantages. Type 1 diabetics probably need to be more careful than type 2 diabetics about this. It's best to ask a doctor.
Post 1

Glucosamine increases blood sugar. That's why people with diabetes are not recommended glucosamine side effects. I wanted to use it but have been avoiding it for this reason.

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