What is Phenylethylamine?

John Markley

Phenylethylamine, also known as 2-phenylethylamine or phenethylamine, is a substance best known for its natural occurrence in the nervous system of humans and other mammals, where it is believed to act as a neurotransmitter or neuromodulator. It has stimulant effects and is important to the neurochemistry of infatuation and romantic love. It is a trace amine and a natural monoamine alkaloid. In the human brain, it causes the release of the neurotransmitters norepinephrine and dopamine. There are also large numbers of derivatives of phenylethylamine, many of which are used medically or recreationally.

The manufacturers of some phenylethylamine supplements purport that the chemical can help people lose weight.
The manufacturers of some phenylethylamine supplements purport that the chemical can help people lose weight.

Phenylethylamine is most prominent for the role it plays during feelings of infatuation, limerence, or romantic love, when it stimulates the release of greater amounts of dopamine and norepinephrine. Dopamine is strongly tied to sexual drive, feelings of pleasure, and the brain's reward system. Norepinephrine causes heightened attention and increased heart rate and is closely tied to the fight-or-flight response. Together, these neurochemicals result in many of the feelings associated with romantic love, including sexual desire, giddiness or euphoria, and nervousness.

Phenylethlamine plays a prominent role in the feelings of infatuation.
Phenylethlamine plays a prominent role in the feelings of infatuation.

There has been speculation that consuming foods that naturally contain large amounts of phenylethylamine, such as chocolate, might mimic these effects or have other psychological benefits. Similarly, pills with the neurotransmitter are often marketed due to the chemical's supposed weight-loss benefits or effects on mood. However, phenylethylamine consumed via the digestive system is metabolized too rapidly for significant amounts to reach the brain, so ingesting it in food, pills, or supplements is typically unlikely to have therapeutic effects. People who suffer from attention deficit-hyperactivity disorder or clinical depression often have lowered levels of phenylethylamine, while schizophrenia sufferers have elevated levels.

Some antidepressants and decongestants contain phenylethylamine.
Some antidepressants and decongestants contain phenylethylamine.

There is are many chemical compounds, collectively called phenethylamines, based on phenylethylamine's chemical structure with atoms added or substituted. These include the categories of substituted phenethylamine, substituted amphetamines, and substituted methylenedioxyphenethylamines. Many of the chemicals in these groups have significant effects on the human nervous system and are used as psychoactive drugs, including amphetamine, methamphetamine, and methylenedioxymethamphetamine, better known as MDMA or ecstasy. The use or possession of some phenethylamines is restricted or banned in many jurisdictions. Some phenethylamines also have medical uses and are used in decongestants, antidepressants, and in treatments for respiratory problems such as asthma.

Chocolate, which contains phenylethylamine.
Chocolate, which contains phenylethylamine.
Amphetamine diet pills suppress hunger while acting as a stimulant.
Amphetamine diet pills suppress hunger while acting as a stimulant.
Phenylethylamine causes the release of norephinephrine and dopamine in the human brain.
Phenylethylamine causes the release of norephinephrine and dopamine in the human brain.
Some phenethylamines may be used to treat asthma.
Some phenethylamines may be used to treat asthma.
Children and adults who suffer from attention deficit hyperactiviity disorder (ADHD) typically have low levels of phenylethylamine.
Children and adults who suffer from attention deficit hyperactiviity disorder (ADHD) typically have low levels of phenylethylamine.
Phenylethylamine plays a role in feelings of sexual desire.
Phenylethylamine plays a role in feelings of sexual desire.

You might also Like

Readers Also Love

Discussion Comments

anon992706

It is pointless to take PEA without supplementing with hordenine.

maja

Can you help me? What is the difference between Phenylethylamine and Phenylethylamine HCL? I've read that it is used for wight loss (it is the main ingredient in PhenObestin - a weight-losss supplement) and I am curious to know whether it really works.

krayphysh

If you're curious as to how Phenylethylamine works for you, make sure you find a good, safe source. I personally recommend Liftmode's PEA, as they always ship promptly and is pure and not tampered with! I can verify that Liftmode offers pure PEA and that this article perfectly sums up its effects!

anon310628

Would using sudafed (pseudoephedrine) for sinusitis be a problem when also taking Phenylethylamine?

Post your comments
Login:
Forgot password?
Register: