What Is Indomethacin Gout Treatment?

Article Details
  • Written By: C. K. Lanz
  • Edited By: Melissa Wiley
  • Last Modified Date: 13 October 2019
  • Copyright Protected:
    Conjecture Corporation
  • Print this Article
Free Widgets for your Site/Blog
In 2019, a winery in Moldova hosted a 10-km race in the world's largest wine cellar, which holds 2 million bottles.  more...

November 19 ,  1863 :  The Gettysburg Address speech was delivered.  more...

Indomethacin gout treatment involves treating an acute gout attack and preventing future recurrences with a prescription nonsteroidal anti-inflammatory drug (NSAID) called indomethacin. The American Federal Drug Administration approved indomethacin for use in the United States in November 2010. For indomethacin gout treatment, the drug is typically administered orally via a 75-milligram extended release capsule. Like other NSAIDs, indomethacin can help control inflammation and reduce pain in individuals with gout.

First described in 1963 in the British Medical Journal, in general terms indomethacin is a prescription drug that halts the body’s production of prostaglandins, a substance that causes inflammation and pain. It is usually administered to relieve moderate to severe pain, tenderness, and swelling caused by various arthritic conditions. The drug is also used to treat tendinitis and bursitis, among many other similar conditions.

This medication is usually prescribed as a 75-milligram extended release capsule taken orally, but liquid and suppository forms are also available. Other dosage forms include injection, topical gel, and patches. Most forms of this drug are typically taken two to four times a day.

Gout is a form of arthritis that often affects the big toe’s base joint. The attacks of pain, joint tenderness, and redness are often sudden and severe. Indomethacin gout treatment aims to treat the immediate acute attack by controlling inflammation and pain while preventing a future recurrence.


Like all NSAIDs, indomethacin gout treatment carries risks. People who take this medication may have an increased risk of stroke or heart attack. Additional side effects include bleeding or holes in the stomach or intestine and ulcers.

Patients should tell their doctors if they or anyone in their family has or has had heart disease, stroke, or a heart attack. High cholesterol, high blood pressure, and diabetes are other conditions that patients and doctors should consider before beginning indomethacin gout treatment. The risks can be especially pronounced if the patient is more than 65 years of age or has been taking an NSAID for a long period of time.

Patients undergoing an indomethacin gout treatment regimen will often be subject to regular physical examination to monitor for side effects. These examinations will look for signs of any changes in the central nervous system as well as edema. Blood pressure, blood cell count, and liver enzymes are also likely to be monitored.

In addition to indomethacin gout treatment, the condition can be targeted with colchicine, corticosteroids, and drugs that affect uric acid production. Colchicine is given to patients unable to take NSAIDs and helps reduce gout pain, but is associated with debilitating side effects like diarrhea. Corticosteriods can be taken orally or injected and control both inflammation and pain. Finally, a doctor may prescribe medication that either blocks uric acid production or increases the kidneys’ ability to remove it from the body.


You might also Like


Discuss this Article

Post 3

I know it sounds strange that the treatment for really intense joint pain would be sticking a needle into your body, but acupuncture has been shown to work wonders for some patients who have gout pain. My mother has these acupuncture treatments for her arthritis.

Post 2

@mobilian33 - I do not have gout, so I can't know what gout pain is like. However, like you, I have a few family members who have the condition, and I have heard from them about the struggles they have endured and continue to have.

My uncle was a social drinker for most of his adult life, and on the weekends he would sometimes drink more than he should have. He says that since he stopped drinking he has fewer gout attacks. He has also cut out many of his favorite foods because many of them are listed as foods to avoid for people with gout.

Post 1

I have a history of gout in my family. My grandmother had the condition and it really limited the things she was able to do as she got older and experienced the flare ups. Her feet would get extremely red, and swollen. They looked terrible. She would get the severe pain in the big toe joint, but what was worse was that the bottoms of her feet hurt when she walked, so she was unable to get around, and eventually used a wheelchair.

I have been using various gout home remedies to help with my condition. Some of them work well for a while, but I have found nothing that has totally eliminated the symptoms. If you have never

had this condition then you can't understand just how stressing it can be. Just when I think I have put the symptoms behind me they come back in full force, as painful as ever. If I had a million dollars I would trade it for a gout cure that would get rid of this discomfort and pain for good.

Post your comments

Post Anonymously


forgot password?