What is Dimethylglycine?

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  • Written By: Deneatra Harmon
  • Edited By: R. Halprin
  • Last Modified Date: 26 July 2018
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The dietary supplement dimethylglycine is a derivative of the amino acid glycine. Dimethylglycine forms in the body as well as in plant and animal life. The supplement reportedly may improve athletic performance and the body's immune system. Foods rich in B vitamins contain at least small amounts of dimethylglycine. Dosages of DMG depend on several factors, and there are few known side effects from taking the supplement.

Also known by other names dimethylamino acetic acid, DMG, and N-methylsarcosine, dimethylglycine is essentially an amino acid, or a building block of protein. Small amounts of this substance can be found in the body. During cell production, the derivative acts as an intermediary in the choline-to-glycine metabolism process. The small intestine absorbs dimethylglycine before it transfers to the liver. Dimethylglycine also appears naturally as a derivative in animal and plant cells.

As a nutritional supplement, DMG reportedly improves sports performance in athletes. Dimethylglycine is also said to function as an antioxidant used to improve the body's immune system. Other claims include DMG as an energy booster and a stress reducer as well as a treatment to control seizures. The supplement apparently lowers blood cholesterol, blood sugar, and blood pressure


The amino acid derivative is also believed to treat symptoms of attention deficit hyperactivity disorder (ADHD) and chronic fatigue syndrome. It is also believed to help those with autism improve in their speech and behavior patterns. Such medical claims, however, have not been proven as effective.

In addition to plant and animal cells, DMG may be found naturally in vitamin B-rich foods. It is also known as vitamin B15. Some of the most common food sources include liver and beans. Cereals, grains, pumpkin seeds, and sunflower seeds also contain specified amounts of the amino acid derivative. DMG may also be found as a liquid supplement or a water-soluble vitamin. DMG is also compatible with other amino acids such as methionine, which helps to prevent fatty artery buildup.

Some doctors may recommend dimethylglycine to address certain health deficiencies. Doses of the amino acid derivative vary based on specific criteria. The proper dosage depends on the person's health, age, and well-being. Some healthcare professionals recommend that patients should not use the supplement longer than 28 days to boost energy and mentality. DMG reportedly may cause drowsiness in some people, although medical evidence has not as yet presented any serious side effects. Before going any on supplement regimen, it is usually best to check with a qualified practitioner first.


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