What is Crenation?

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  • Written By: Mary McMahon
  • Edited By: O. Wallace
  • Last Modified Date: 07 December 2018
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Crenation is a phenomenon which occurs when cells of animal origin are exposed to a hypertonic solution, meaning that the solution which bathes the cells has a high concentration of solutes. In crenation, the cells shrink and their shapes become distorted, often with a ruffled or scalloped edge. The change in cell shape can be seen in microscopy of the cells, and can be a sign that someone is experiencing a medical problem. These cells may die as a result of impairments in cell function.

When animal cells are bathed in a hypertonic solution, it draws water out of the cells through a process known as osmosis. Water flows from areas of low solute concentration to areas of high solute concentration in an effort to stabilize the difference between the two solutions. Sometimes, particles small enough to pass through the cell walls may be drawn out along with the water, and in other cases, they remain behind because they are too big to move through the cell membrane.

As the water leaves the cell, it starts to shrivel, since much of its shape is due to the water inside which keeps it plump. Red blood cells display the results of crenation more markedly, transitioning from a round to a spiky shape. The term “crenation” is a reference to the scalloped shape of a crenated cell. Without water, the cell will have trouble functioning.


One reason the phenomenon occurs is dehydration. When the body is not ingesting more water, the fluid which bathes cells can become hypertonic, rather than isotonic, in which the extracellular fluid and fluid inside the cells has the same concentration of solutes. Crenation can also be associated with some disease processes. The same process is known as plasmolysis in plant cells because the rigid cell wall prevents the cell from changing shape as water is lost.

If the solution is hypotonic, with the fluid inside the cells having a higher concentration of solutes than the fluid which surrounds the cells, water will pass through the cell wall and into the cell as a result of osmosis. If enough water is absorbed, the cell will burst and release its contents. This can be a very serious consequence of drinking large amounts of water without urinating, as the kidneys cannot keep the balance of fluids in the body stable when they cannot eliminate urine.


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Post 3

Erythrocytes are the most common part of blood in vertebrates. It is the primary mode of transportation of oxygen through the body.

These cells travel to the gills of sea creatures or lungs of land creatures and soak up the oxygen. Inside these cells is iron and with a chemical reaction between the iron and oxygen the oxygen is kept safe in the cell until released to the final delivery point.

Erythrocytes live for 100 to 120 days and are then recycled. The human body generates over two million of them per second.

About one quarter of the cells in the human body are red blood cells.

Red blood cells (as part of whole blood) can be donated, to save lives of people suffering a shortage of healthy blood cells. Donating red blood cells can be done every sixty days with little disruption to the human body.

Post 2
Too much of any good thing can be bad, even water. It seems that red blood cell crenation can happen if the kidneys cannot keep up with the intake of water. Also, the brain can swell. Who would have thought even water could be a troublesome thing?

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