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What Is a Contrast Agent?

Mary McMahon
Mary McMahon
Mary McMahon
Mary McMahon

A contrast agent is a substance which is used in a medical imaging study to make it easier to see the internal structures of the body. Numerous different types of contrasts are used; they are sometimes called “dyes” because they appear to dye the tissue which is being studied. If you are scheduled for medical imaging, a radiologist will discuss the use of contrasts with you if one is required. Most agents are very safe, and they will be expressed from the body very quickly after the studies; in rare cases, someone has an allergic reaction.

One of the most common types of contrast agent is an ingested agent like barium sulfate, which is taken by mouth for studies of the gastrointestinal tract. This substance is radioopaque, meaning that x-rays cannot pass through it. As a result, the x-ray film is not exposed, and the doctor has a bright white picture of the patient's intestines. For MRIs, a substance which affects the magnetism of the tissue of interest is used.

A contrast agent can be used to make certain parts of the anatomy stand out more clearly on an X-ray.
A contrast agent can be used to make certain parts of the anatomy stand out more clearly on an X-ray.

A contrast agent can also be injected. A wide variety of agents are used for injection with various types of imaging machines. Injected agents can sometimes be uncomfortable for patients; they may cause a burning sensation or a strange feeling, but they are usually safe. Such agents can illuminate the inner workings of the brain and central nervous system with incredible detail.

A contrast agent may sometimes be inserted through the rectum.
A contrast agent may sometimes be inserted through the rectum.

Contrast agents may also be inserted through the rectum or inhaled for very rare imaging studies. Generally, a radiologist decides on what type of contrast should be used, although the patient record will be consulted to check for any potential allergic risks. The contrast may be given to the patient right before the study, or he or she may be given some additional time to ensure the agent reaches the desired destination; once the contrast agent has suffused the area of interest, the radiologist takes images of the site for later analysis.

A wide variety of contrast agents are used for injection with various types of imaging machines.
A wide variety of contrast agents are used for injection with various types of imaging machines.

The use of a contrast agent is generally very safe for the patient, as most radiologists want to avoid harmful reactions. However, allergic reactions do happen. If an imaging study with contrast is ordered, ask the radiologist about common side effects, and alert him or her if you begin to feel unwell. If the radiologist feels that you may be having an adverse reaction, he or she will take the appropriate steps to treat you.

Mary McMahon
Mary McMahon

Ever since she began contributing to the site several years ago, Mary has embraced the exciting challenge of being a TheHealthBoard researcher and writer. Mary has a liberal arts degree from Goddard College and spends her free time reading, cooking, and exploring the great outdoors.

Learn more...
Mary McMahon
Mary McMahon

Ever since she began contributing to the site several years ago, Mary has embraced the exciting challenge of being a TheHealthBoard researcher and writer. Mary has a liberal arts degree from Goddard College and spends her free time reading, cooking, and exploring the great outdoors.

Learn more...

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    • A contrast agent can be used to make certain parts of the anatomy stand out more clearly on an X-ray.
      By: nyul
      A contrast agent can be used to make certain parts of the anatomy stand out more clearly on an X-ray.
    • A contrast agent may sometimes be inserted through the rectum.
      By: Alexandr Mitiuc
      A contrast agent may sometimes be inserted through the rectum.
    • A wide variety of contrast agents are used for injection with various types of imaging machines.
      By: Lisa F. Young
      A wide variety of contrast agents are used for injection with various types of imaging machines.
    • Contrast MRIs use a substance that reacts with the magnesium in the body.
      By: Mikhail Basov
      Contrast MRIs use a substance that reacts with the magnesium in the body.
    • A radiologist is typically responsible for deciding the type of contrast agent that should be used.
      By: michaeljung
      A radiologist is typically responsible for deciding the type of contrast agent that should be used.
    • In rare imaging studies, contrast agents may be inserted through the rectum.
      By: kocakayaali
      In rare imaging studies, contrast agents may be inserted through the rectum.
    • Signs of an allergic reaction to a contrast agent may include sneezing.
      By: Monkey Business
      Signs of an allergic reaction to a contrast agent may include sneezing.
    • Barium sulfate is a common contrast agent used in studies of the gastrointestinal tract.
      By: graphicgeoff
      Barium sulfate is a common contrast agent used in studies of the gastrointestinal tract.