What Is a Ciprofloxacin Allergy?

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  • Written By: Andrew Kirmayer
  • Edited By: Shereen Skola
  • Last Modified Date: 02 February 2019
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Ciprofloxacin is a common medication used to treat bacterial infections. Many bacteria, causing conditions ranging from urinary infections to Anthrax can be killed using the antibiotic. The drug itself can be dangerous for anyone who has a ciprofloxacin allergy. There are a number of signs that somebody might have an allergy to it, including a rash and a number of possibly life-threatening ailments that could be fatal if not treated quickly. Any one of the drug’s side effects can be exacerbated by the presence of an allergy or treatment with other medications.

Allergies to antibiotics should be considered a reason to avoid taking this drug, as the associated risks and possible ciprofloxacin drug interactions could be magnified. A common sign of a ciprofloxacin allergy is if the user sees hives or swelling. Effects such as this usually occur on the face or throat, possibly interfering with breathing, and severe diarrhea and difficulty urinating also can indicate a severe reaction. The side effects of ciprofloxacin that are considered less dangerous may not be caused by an allergy. Nausea or vomiting, dizziness, nervousness, or blurriness in the eyes should still be reported to a doctor.


A true ciprofloxacin allergy can include itching, rashes and blisters on the skin. It can also affect the joints in painful ways and it might be impossible to move certain joints as a result of the allergy and side effects. Fainting, hallucinations, depression, and even seizures can result from a ciprofloxacin allergy as well.

To avoid allergic reactions to the antibiotic, it is important for patients to let a physician know information including known allergies to other medications. Allergies to other similar medicines could be a good indication that taking ciprofloxacin is not a good idea, and current medications should also be considered, including those given to treat heart rhythm disorders.

It is also important for a ciprofloxacin user to know the proper dosage prior to starting treatment. If the correct amount is taken and reactions occur, then it is considered to be an allergy and not an overdose, which can be highly dangerous and needs to be treated differently. Any ciprofloxacin allergy can progress very rapidly so patients who start to have reactions are advised to contact a doctor immediately. Physicians often conduct tests on patients prior to prescribing this medication, in order to see if any serious reaction could occur before the antibiotic is taken.


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Post 7

I am experiencing a prickly body rash - face, neck, torso back, arms from head to my knees in a splotchy red and spotted rash after completing my 10 days of cipro for diverticulitis.

Got to a Minute Clinic on Sunday and they gave me pill form of prednisone. I've been on it for two days and Benedryl every six hours. The rash has worsened during this time. I'm on a work trip, so leaving for home tomorrow to see my doctor. No other side effects for now..

Post 5

I finished a 10 day course of Cipro for diverticulitis. Two days later I was covered in hives and itching from head to toe. It also has affected my breathing ( I do have asthma ) I have muscle and joint pain. This is week two and no end in sight. What to do?

I am now on my eighth day of Prednisone, which is helping, but I'm still experiencing some itching and hives and lots of breathing difficulties and pain. I was fine before the Cipro except, of course, for the diverticulitis. My asthma had been under great control before the Cipro.

Post 4

I took just one tablet this afternoon and within 30 minutes, my eyes started to burn and were becoming itchy. I went to bed but was feeling uneasy, so I went to the bathroom, only to find out when I looked in the mirror that I had swollen eyes. I had baggy eyes all day and still am very itchy. I am now scared to take the second dose. Is this a severe allergy or a common side effect?

Post 3

I'm allergic to ciprofloxacin. I found out when I was prescribed it for an ear infection last summer. I broke out in hives soon after I took it.

Post 2

@burcinc-- Is diarrhea the only symptom you're experiencing?

If so, I wouldn't worry about it. I get diarrhea from antibiotics all the time. It's considered a common symptom unless it's so severe that you're getting dehydrated and if you have additional symptoms like vomiting, rash, itching, difficulty breathing and so forth.

Antibiotics cause diarrhea and other gastro-intestinal side effects because it upsets the bacterial flora in the stomach and intestines. I suggest taking a probiotic supplement (or eating lots of yogurt) while on antibiotics to prevent this.

Usually diarrhea, vomiting and nausea are signs of sensitivity or intolerance to medications. An allergy will cause hives, itching and difficulty breathing.

I'm not an expert though, so if you're not sure, please call a pharmacist to double check.

Post 1

I'm on a seven day course of ciprofloxacin. After the second day, I started getting diarrhea and I'm on the fourth day now.

Is this an allergy? I can't reach my doctor and he told me to finish the entire course. I don't know what to do.

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