What Are the Signs of an Allergic Reaction to Vitamins?

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  • Written By: Valerie Goldberg
  • Edited By: Angela B.
  • Last Modified Date: 25 May 2019
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While it is more commonly accepted that a person can have an allergic reaction to prescription medications, many people don't realize that it also is possible to have an allergic reaction to vitamins. Both multivitamins and specific vitamins such as B and D can cause reactions in some people. The most common signs of a vitamin allergy include hives, facial swelling, skin irritation and vomiting, among others.

A person who experiences an allergic reaction to multivitamins may break out in itchy hives. While most hives are an itchy nuisance, it is possible to develop hives in one's throat, which can cause breathing problems along with the discomfort. Antihistamines and calamine lotion can be used to help treat any discomfort the external hives are causing, but any indication that hives have developed in the throat requires immediate medical attention.

Facial swelling is another common allergic reaction to vitamins. If a person begins taking a new multivitamin and experiences swelling in the face or tongue, then it can be a sign of a very serious allergic reaction. A person who feels as if his or her throat is closing or that he or she cannot breathe shortly after consuming a multivitamin should be taken to an emergency room as soon as possible.


A person should be aware of the possibility of having an allergic reaction to vitamins if he or she is beginning to take a specific vitamin. Vitamin B is a popular vitamin among people looking to have healthy hearts or ease the symptoms of severe anxiety. A person who begins taking vitamin B and notices a skin rash may be allergic. Nausea, vomiting and other stomach troubles also may be signs of a vitamin B reaction. If a person believes he or she is allergic to vitamin B supplements, then he or she should stop taking the pills and make a doctor's appointment to talk to his or her healthcare provider about the symptoms.

A patient with a lot of food allergies may stand an elevated chance of being allergic to vitamin C, vitamin D and other popular supplements. A person who is concerned about a potential vitamin allergy can arrange an appointment with an allergist for testing. An allergist can perform a skin patch test to learn which vitamins, if any, present a problem for a person. Doing a skin patch test upfront can save a person from suffering a severe allergic reaction to vitamins later on. Discussing with a doctor the addition of vitamins to a daily health routine can help to prevent allergic reactions before they start.


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Post 6

I will try to decrease my vitamins to 3 times a week to see if my skin trends to getting better. I eat pretty healthy and maybe I am overdoing it with the vitamins and minerals.

Post 5

I started just this past Friday (its now Tuesday) the Alive Energy for Woman multi and now I have hives on my back. There are just about 10 or so, and they don't itch, but its definitely from this vitamin.

I tried the same vitamin last year and had a similar reaction but my dermatologist told me it was highly unlikely it was that. However, now I know it's the vitamin. I emailed my dermatologist and she looked up the ingredients and seems to think that its a combo of the fruit and veggies that are included in them. Terrible.

Post 4

I took One a Day multi and blew out in hives in three days. I was very itchy but had none in my throat. I quit them two days ago, but the hives are still present. I'm waiting for them to subside.

Post 3

I developed a rash after taking a multivitamin last night. The rash disappeared on its own, but I can't take the supplement again. And I have no idea which vitamin I'm allergic to.

Post 2

@ZipLine-- You might not be allergic to vitamin C. You might just be allergic to the form of vitamin C in the supplements. Or you might be allergic to the additives found in the supplements.

Do you have similar symptoms when you eat foods that are high in vitamin C, like oranges? If not, try to get your vitamin C through food instead. Trying a different supplement brand might also be a good idea. Always use high quality and natural supplements from reliable brands.

At this point though, you should get an allergy test before taking any more supplements. Sometimes an allergy starts out mild but can become worse fairly quickly.

Post 1
I started taking vitamin C supplements after my doctor recommended them, but I've noticed that I have seasonal allergy like symptoms when I take them. I get a runny nose and runny eyes and I sneeze.

I stopped taking them yesterday and the allergy symptoms are gone. I can't believe that I'm allergic to vitamin C. How is this possible?

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