What Are the Different Simethicone Side Effects?

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  • Written By: T. Carrier
  • Edited By: John Allen
  • Last Modified Date: 22 February 2020
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Simethicone is a class of pharmaceutical drugs primarily used for the treatment of gas and bloating. This medication may be taken in several forms, ranging from liquid drops to chewed or crushed tablets. Unlike many medicines, simethicone products seemingly possess no significant side effects. Exceptions do exist for simethicone side effects in certain cases, such as allergic reactions, overdose, or use by pregnant women. Severe effects in these cases might include swelling, rashes, and respiratory problems.

Side effects generally include any effect a substance has that differs from its primary effect. Typically, these effects are undesirable physical ailments like nausea or headache. Many medications list common side effects on their labels. If a particular adverse reaction occurs in a clinically significant portion of patients, then it will likely be a part of this list.

No clinically significant simethicone adverse effects have been reported. This does not mean, however, that all patients will remain side effect-free. It simply means that within the known patient studies and reports, the primary percentage of simethicone users have not indicated any major problems. The lack of simethicone side effects is likely owed to the bloodstream’s non-absorption of the substance.


This deficiency of simethicone side effects may potentially aid patients beyond comfort level. If a patient does experience certain discomforts like stool problems or abdominal pain, then the physician might be alerted of an underlying condition. Any negative effects associated with simethicone should be evaluated by a medical professional, particularly in the case of severe allergic reactions.

One way a patient may experience simethicone side effects is via allergic reactions. Some individuals have abnormalities in their immune systems. Due to this abnormality, immune agents will mark certain substances as harmful foreign particles even if said substances are intended to help the individual. As a consequence, the body produces defensive responses when it encounters the substance. For allergic side effects of simethicone, these responses might include the following: facial swelling, itchy rashes, chest pressure, and breathing problems.

Certain conditions also increase the possibility of experiencing negative simethicone side effects. Pregnant women are advised against taking the substance, as it may cause harm to a developing fetus. In addition, simethicone interaction may worsen certain aspects of a genetic metabolic condition known as phenylketonuria.

Like most medications, the recommended simethicone dose should be respected as well. Medical professionals, for example, usually advise patients not to exceed more than 500 milligrams in a day. Separate dosages may range anywhere from 60 milligrams to 180 milligrams for adults. Dosages for children will vary. Any overdose is serious, as it may require the attention of a poison control center.


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