What are Lysine Benefits?

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  • Written By: K.C. Bruning
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The essential amino acid Lysine helps to build protein in the body. Some lysine benefits include formation of collagen, a strengthened immune system, and helping the process of converting food to energy in the body. When it is used as a supplement, one of the primary lysine benefits is in the effective treatment and prevention of cold sores specifically and the herpes virus in general. Another of the reported lysine benefits is an improvement in athletic performance, though this has not been clinically proven.

Lysine is one of eight essential amino acids that are not produced by the body. A well-balanced, healthy diet can provide the body with all of the lysine it needs. In order to boost lysine benefits, it can also be taken as a supplement, either orally or as a topical cream.

The essential benefits of lysine include formation of collagen, strengthening of the immune system, and aiding in the process of converting food to usable energy. Collagen is found in tendons, cartilage, ligaments, and bones, all of which need lysine to properly absorb the calcium required to build these parts of the body. Lysine also helps the body to make the antibodies that boost the immune system. As an important part of the chain of events that turns food into energy, lysine is a precursor for the amino acid L-carnitine in the conversion process.


Taking lysine supplements benefits patients with cold sores, also known as herpes simplex labialis, by reducing the healing time and severity of the sores and preventing the growth of new sores. It is often prescribed as a general herpes treatment because it appears to stop the growth of the virus. Body builders also take the supplement, but it has not been proven that lysine benefits athletic performance

Side effects from taking lysine supplements are rare. They include diarrhea, abdominal cramps, and stomachache. Though not common, there has been one known instance of kidney disease that was connected with use of a lysine supplement. Animal studies have shown that taking high doses of lysine can cause gallstones. As not much is known about the effect of lysine on pregnant and nursing women, it is advised that they avoid taking the supplement.

A diet without adequate lysine can lead to hair loss, anemia, low energy, poor appetite, and difficulties concentrating. Lysine deficiency can also lead to delayed growth and disorders of the reproductive system. Vegetarians are at a higher risk for lysine deficiency and must balance their diets to ensure proper consumption of all essential amino acids. Lysine can also be destroyed if food is cooked at an excessively high temperature.


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Post 3

I take lysine supplements at the onset of a cold sore blister. When I start feeling tingling on my lip, I reach for the lysine. If I take it on time, I can prevent blisters. Even if I take it late, the blister heals faster with lysine. The only downside is lysine side effects. It gives me diarrhea if I take it for over a week.

Post 2

@SarahGen-- I just started using l-lysine for this purpose. L-lysine has many benefits because it's an essential amino acid required by many different cells in our body. Hair also contains l-lysine, so it can definitely improve the quality of hair and reduce hair loss. Unfortunately, it's not a well known fact. It also doesn't help that there aren't many studies being done on this connection. And many people are not willing to try something if they don't see many studies proving that it works.

However, it works for my sister and I've started seeing results as well. In the recommended dose, l-lysine doesn't have much side effects and it's available at all pharmacies. So it wouldn't hurt to try it. I recommend combining it with biotin supplements. That's what I'm doing.

Post 1

Has anyone heard of l-lysine being used for hair loss? Or has anyone here used it for this purpose?

I actually heard about this on TV but I'm not sure if there is any truth to it. I've heard of l-lysine being used to prevent illness in winter and to help cold sores heal. But I have never heard of any connection between l-lysine and hair loss. Is there one?

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