One of the most important things you can do when choosing a motherboard is to get one that has way more RAM than you'll ever think you need. Max out that RAM and you may have a motherboard that will last for years.
Why? As operating systems and programs get more sophisticated, more RAM is needed to keep everything running quickly. That motherboard that might be sufficient today might be junk down the road because it you won't be able to add enough RAM to it to meet the needs of the programs you will want to use.