I read in an article that the main cause of homeostasis going off balance is stress. I also know that stress is a main cause of disease. So clearly, these three things are closely related.
I don't know if stress causes disease first and then an imbalance in homeostasis or the other way around. But I think we can probably draw the conclusion that it's difficult for our body to remain in homeostasis and avoid diseases when we are under stress. Stress weakens the immune system, that's must be why.
What do you guys think?