What Is the Dermal Papilla?

Androgen receptors, which are responsible for male pattern baldness, and found in the dermal papilla.
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  • Written By: Amanda Barnhart
  • Edited By: C. Wilborn
  • Last Modified Date: 14 March 2015
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The dermal papilla is a group of cells that form the structure directly below the hair follicle. These cells supply glucose to the follicle, which is needed for energy and the production of amino acids. This nourishment allows the body to grow new hair.

Receptors for androgens are found in the dermal papilla. Androgens are hormones responsible for hair growth, among other body funcitons. Individuals who have a genetic predisposition to baldness or hair loss may notice that their hair gets increasingly thinner. Androgens can cause hair follicles on the scalp to get smaller, leading to hair thinning and progressing baldness.

The dermal papilla begins to form while a human baby is still in the womb. They begin development by the time an embryo is three months old. They mark the spot for hair follicles that will grow hair later, both in the womb and after birth.

When the hair follicle is in the anagen phase, the dermal papilla is large and the cells are spaced far apart. This opens up the hair follicle so that it can receive energy and keratin, the protein that makes up hair, from the dermal papilla to promote new hair growth. At any given time, about 85 percent of hairs on the human body are in the anagen, or growing, phase.


Hair follicles can stay in this phase for up to six years. After the growth phase is over, the hair follicle enters a transitional phase called the catagen phase for one to two weeks. The follicle gets smaller, to around 1/6 of its previous size, during this transition phase, and the dermal papilla breaks off. The cells flatten and move in together to form a dense ball.

The hair follicle rests in a phase called the telogen phase for about five to six weeks following the transitional phase. Hair does not grow during the resting phase, and the dermal papilla cells remain in a tight cluster below the follicle. Once the hair follicle returns to the growing phase again, the dermal papilla joins with the hair follicle above and initiates new hair growth by providing the follicle with nourishment.



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Post 3

@ Sun Seal

So is there some way to truly stimulate the androgens? A way that isn't just a bunch of marketing nonsense for desperate people? Hair loss prevention is a big deal, but what if you've already started losing it?

Post 2

@ Copper Salmon

I think it's the androgens. The article says that the androgens cause hair follicles to get smaller over time and that eventually leads to baldness. I just turned 45 and I'm noticing a thinning patch right on the back of my head. My girlfriend was too nice to tell me about it and when we went shopping, I saw it in one of those 3 sided dressing room mirrors. Totally shocked! I'm considering the head shave myself.

Post 1

Okay, so is it that the receptors or the androgens that aren't working properly and cause hair loss? Is there anyway to trick the receptors and androgens to work correctly? If I lose much more hair, I'm going to shave it all off. No way am I doing the Michael Bolton long hair-bald on top thing or the comb over.

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