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What Is Serositis?

Serositis is the medical term for an inflammation of the lining of the lungs, heart, or abdomen and abdominal organs. The tissues that form the linings of these body parts are called serous tissues, and they form sacs around these important organs. An additional important function of the serous tissues is the secretion of lubricating fluid. Serositis symptoms are usually seen along with other symptoms in sufferers of various severe inflammatory illnesses, and can cause significant discomfort or pain.

There are a number of diseases in which serositis is a diagnostic or commonly occurring symptom. These include Crohn’s disease, lupus, Familial Mediterranean fever, and juvenile arthritis. All of these are in large part inflammatory diseases, and either acute serositis, or chronic serositis may be experienced.

Crohn’s disease is an inflammation of the intestines caused by an autoimmune response. Abdominal serositis in Crohn’s disease patients is a key symptom. Sometimes, the disease also results in an inflammation of the lining of the lungs, or of the lung sacs.

Inflammation symptoms in lupus commonly take the form of pericarditis, inflammation of the heart membrane, or pleurisy, which is inflammation of the lung sacs. Chest pains are usually experienced in either case. One or both of these types of inflammations are usually seen in nearly half of lupus patients, and they are some of the most important indicator symptoms of lupus, although doctors will normally rule out other root causes of the inflammation prior to making a diagnosis.

In Familial Mediterranean fever, inflammation may occur in the lungs, heart, abdomen, or all three. This hereditary disease results in attacks of acute inflammation that may be very painful, and can last for several days at a time, usually accompanied by a raised temperature. Abdominal attacks of Familial Mediterranean fever have been known to be misdiagnosed as appendicitis, with resulting unnecessary removal of the appendix.

Juvenile arthritis may be accompanied by serositis symptoms. This is usually seen in particular in patients suffering from systemic juvenile idiopathic arthritis (JIA), a painful condition characterized by arthritis with recurrent fever and rashes. In serious cases, internal organs may become inflamed, leading to pericarditis, and other serious inflammations.

The treatment of serositis usually depends to a great extent on the underlying disorder of which it is a presenting symptom. Anti-inflammatory drugs may be used, along with pain relief medication, to alleviate the symptoms. In some cases, steroids may be prescribed.

Written by C. Martin