Alkaptonuria is a scary disease. I was really young then, but I do remember my grandmother who had all the ochronosis symptoms. Especially towards the end of her life, her hands, eyes and ears had become really blue.
At least now, laser treatment is available for people who suffer from this. But in those years, there was basically no treatment whatsoever. And people just had to watch their symptoms get worse. My grandmother didn't let it get to her, but I'm sure she would have had she been younger.
I hope in the future, more treatments can be found for alkaptonuria and orchronosis. I would especially like to see this happen for kids who suffer from these symptoms.