I don't know what the traditional muffaletta lovers would think about this but there are now vegetarian and vegan versions of the muffaletta sandwich. Instead of being made with charcuterie items like salami, the vegetarian version is made with assorted veggies. I think the one common item in both is the olive spread.
I think that as more people have preferred to eat vegetarian and vegan, specialty grocers and sandwich shops are trying to cater to those customers as well and have started making vegetarian versions of everything.
I've had the vegetarian muffaletta sandwhich both at a shop and homemade and I think it's delicious. I can't say that it is better than the original because the original just has a different taste from the meat. But it's quite good for a vegetarian muffaletta, especially with fresh bread, homemade olive spread and fresh organic veggies like bell peppers and mushrooms.