Ipratropium bromide nasal spray is a medication used to treat symptoms of perennial rhinitis, such as a runny nose. Ipratropium bromide is also an ingredient in asthma inhalers and is often one of the drugs prescribed along with albuterol to treat asthma. When it is prescribed in the form of a nasal spray, it is intended to treat only rhinitis, not asthma.

The nasal spray is indicated for runny noses, which may be caused by allergies or a cold. Ipratropium bromide nasal spray does not treat other symptoms of a cold such as cough, nasal congestion, or sneezing. It is approved by the United States Food and Drug Administration (FDA) for adults and children over the age of six.

It is classified as an anticholinergic drug. When it is used as a nasal spray, it reduces the amount of mucus. It works by reducing how much fluid is produced in the nasal passages.

Ipratropium bromide nasal spray is available with a prescription from a doctor and not available over the counter. Although dosage may vary, most people are prescribed two sprays in each nostril up to three times a day while they have a runny nose. Pediatric doses may be less.

When first using the nasal spray, it must be pumped seven times to prime it for use. If the spray is not used for a week, it should be primed again with seven sprays. When priming the pump, users should point it away from the face to prevent the medication from going into the eyes or lungs.

Unlike asthma inhalers, the nasal spray is not meant to be inhaled deeply into the lungs. It is simply sprayed into the nostrils. It works when it comes in contact with the lining of the nasal passages. One nostril should be held closed while using ipratropium bromide nasal spray. After spraying the medication, patients should sniff in without inhaling too deeply.

Side effects can occur with ipratropium bromide nasal spray. The most common side effects are dry nose, nosebleed, and headache. Some people using ipratropium bromide nasal spray may also experience blurred vision.

It is also possible to develop nasal congestion and a sore throat when using the medication. Taste changes and nausea are unlikely, but can occur. Occasionally, some people may have an increase in heart rate, however, this is also rare. When the medication is used longer than recommended or at higher doses than recommended, there is an increased likelihood of certain side effects, such as nasal irritation.