@ddljohn-- I think the horse chestnut cream sold in he US is fairly safe. I have been using it for a month and have not noticed any adverse side effects.
It doesn't seem to do a lot for vericose veins, or perhaps it takes a long time to show effects in that area. Vericose veins are difficult to treat, so that's not surprising.
Horse chestnut cream is fantastic for leg and ankle swelling however. And it also helps with skin discoloration. I tend to experience edema when I stand up for long hours. An application of horse chestnut cream after arriving home relieves the swelling and pain. So I like it for that.