Category: 

What is Fibromuscular Hyperplasia?

Article Details
  • Written By: J.M. Willhite
  • Edited By: Heather Bailey
  • Last Modified Date: 20 September 2016
  • Copyright Protected:
    2003-2016
    Conjecture Corporation
  • Print this Article
Free Widgets for your Site/Blog
The atmosphere of Jupiter's moon Io collapses every time it is eclipsed by the planet.   more...

September 29 ,  2008 :  The Dow Jones Industrial Average experienced its largest one-day drop in history.  more...

Fibromuscular hyperplasia, also known as fibromuscular dysplasia (FMD), is a serious medical condition that affects arterial physiology and function. Commonly affecting the renal arteries, fibromuscular hyperplasia is defined by unchecked cell production, known as dysplasia, which results in a thickening of the affected tissues. The subsequent arterial narrowing places one at significant risk for complications. In the absence of a cure, fibromuscular hyperplasia may be treated with a combination of medications and surgery.

Arterial constriction and hyperplastic symptoms associated with this condition can mimic the effects of atherosclerosis. Therefore, determining the exact cause of one’s symptoms is essential to appropriate treatment. Generally, imaging tests are used to diagnose fibromuscular hyperplasia. Arterial condition, functionality, and circulation are generally evaluated using ultrasound and angiogram technologies.

Fibromuscular dysplastic symptoms present when cellular reproduction within an arterial wall occurs unchecked. As the cells multiply within the confines of the soft tissue, the excess cells serve no purpose. The unnecessary cells accumulate, thickening the tissue and forming a bulge that narrows the arterial passage, ultimately, impairing blood flow.

Ad

Despite the absence of a known cause for disease onset, several factors may contribute to fibromuscular hyperplasia. Acquired or congenital arterial malformation that jeopardizes oxygen delivery to the arterial walls may facilitate hyperplastic activity. A genetic link may also be possible since multiple members of a single family may develop FMD symptoms. Tobacco use is also frequently considered a contributory factor due to its effects on blood oxygen levels and arterial health.

In most cases, individuals with fibromuscular hyperplasia remain asymptomatic, meaning they show no signs of illness. Symptom presentation is generally dependent on the location of the arterial dysplasia. Individuals with fibromuscular hyperplasia may develop localized discomfort, atrophy or loss of function, and unintended weight loss. When the arterial dysfunction resides in the extremities, impaired blood circulation may cause numbness, skin discoloration, and the affected area to feel cold to the touch.

If signs of FMD are ignored or treatment is delayed, significant complications may result. Impaired blood flow necessitates increased force to keep the blood circulating, triggering an increase in one’s blood pressure. Areas where the dysplastic activity is most prominent can become weakened, leading to aneurysm development. Compromised circulation may also increase one’s chance for a stroke and jeopardize organ function.

Medications designed to ease arterial constriction, reduce heart rate, and flush excess fluids from the body are generally prescribed for fibromuscular hyperplasia. Angioplasty is usually performed using a balloon catheter to widen the affected artery. The presence of aneurysmal tissue can necessitate stent placement to prevent arterial collapse. Long-term drug therapy is generally recommended following surgery to minimize the possibility for future procedures.

Ad

You might also Like

Recommended

Discuss this Article

FMDAdvocate
Post 1

Thank you for helping educate and spread information about FMD, Fibromuscular Dysplasia.

Post your comments

exception 'Exception' with message 'error writing captcha: Duplicate entry '2147483647' for key 'PRIMARY'' in /ssd/www/wisegeek/public_html/_core/classes/public/Captcha.php:44
Stack trace:
#0 /ssd/www/wisegeek/public_html/_core/controls/public/ControlDiscussionPostBox.php(324): Captcha->createCaptcha()
#1 /ssd/www/wisegeek/public_html/framework/classes/Control.php(104): ControlDiscussionPostBox->preRender(false)
#2 /ssd/www/wisegeek/public_html/framework/classes/Control.php(149): Control->render()
#3 /ssd/www/wisegeek/public_html/tpl/default-nocustom-lu/pages/public/article/article.htm(526): Control->__toString()
#4 /ssd/www/wisegeek/public_html/framework/classes/Control.php(300): require('/ssd/www/wisege...')
#5 /ssd/www/wisegeek/public_html/framework/classes/Control.php(309): Control->requireTpl('pages/public/ar...', Object(PageArticleCom), true)
#6 /ssd/www/wisegeek/public_html/framework/classes/Control.php(131): Control->renderTpl('pages/public/ar...', Object(PageArticleCom))
#7 /ssd/www/wisegeek/public_html/framework/classes/FormDataControl.php(87): Control->renderTemplate()
#8 /ssd/www/wisegeek/public_html/framework/classes/Control.php(109): FormDataControl->renderTemplate()
#9 /ssd/www/wisegeek/public_html/framework/classes/ScriptPage.php(50): Control->render(false)
#10 /ssd/www/wisegeek/public_html/framework/classes/Control.php(149): ScriptPage->render()
#11 /ssd/www/wisegeek/public_html/framework/classes/Page.php(97): Control->__toString()
#12 /ssd/www/wisegeek/public_html/_core/classes/public/PublicFrontController.php(443): Page->processRequest()
#13 /ssd/www/wisegeek/public_html/_core/classes/public/PublicFrontController.php(7): PublicFrontController->renderPage()
#14 /ssd/www/wisegeek/public_html/index.php(11): PublicFrontController::run()
#15 {main}