What is DNA Fingerprinting?


DNA fingerprinting is a way of identifying a specific individual, rather than simply identifying a species or some particular trait. It is also known as genetic fingerprinting or DNA profiling. As a technology, it has been around since at least 1985, when it was announced by its inventor, Sir Alec Jeffreys. DNA fingerprinting is currently used both for identifying paternity or maternity and for identifying criminals or victims. There is discussion of using DNA fingerprinting as a sort of personal identifier as well, although the viability of this is debatable.

The vast majority of a human's DNA will match exactly that of any other human, making distinguishing between two people rather difficult. DNA fingerprinting uses a specific type of DNA sequence, known as a microsatellite, to make identification much easier. Microsatellites are short pieces of DNA which repeat many times in a given person's DNA. In a given area, microsatellites tend to be highly variable, making them ideal for DNA fingerprinting. By comparing a number of microsatellites in a given area, one can identify a person relatively easily.

The sections of DNA used in DNA fingerprinting, although highly variable, are passed down from parents to their children. Although not all of the sections will necessarily be passed on, no child has pairs that their parents do not have. This means that by comparing large groups of these sections, paternity, maternity, or even both, may be determined. DNA fingerprinting has a high success rate and a very low false-positive rate, making it an extremely popular form of paternity and maternity verification.

In forensics, DNA fingerprinting is very attractive because it doesn't require actual fingerprints, which may or may not be left behind, and may or may not be obscured. Because all of the DNA sections are contained in every cell, any piece of a person's body, from a strand of hair to a skin follicle to a drop of blood, may be used to identify them using DNA fingerprinting. This is useful in the case of identifying a criminal, because even a drop of blood or skin left at the crime scene may be enough to establish innocence or guilt, and it is virtually impossible to remove all physical trace of one's presence. DNA fingerprinting is useful in the case of identifying victims because even in cases where the body may be disfigured past identification, and teeth or other identifying features may be destroyed, all it takes is a single cell for positive identification.

DNA fingerprinting is by no means perfect, however. It cannot establish beyond the shadow of a doubt that a specific cell comes from a specific person; it can only establish a probability. In many cases this probability is very high -- one in ten billion, for example -- but in some cases it may be much lower. The probability also becomes obscured when dealing with direct descendents, who may share a large portion of the examined areas of DNA with a parent.

Despite these problems, DNA fingerprinting is becoming more and more prevalent in the world of criminal forensics. Though some legal questions exist, such as the conclusiveness of DNA fingerprinting and the extent to which it is legal by national laws to compile databases of people's DNA and to take samples of their DNA for comparison, the benefits currently seem to outweigh the problems.

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23
I'd just like to say that no you can't change your fingerprints but the good news is not everyone has the same fingerprint.

i study forensic science and so far i can tell you that everyone has their own unique fingerprint. dna can tell you what your blood type is because dna is in your blood cells, and to answer anon48668's question about the rape, yes the sperm can get traced back if at early staged otherwise the answer is no.

And to anon52828's question, it is used a lot but the problem with fingerprinting is that you cannot convict someone with just the fingerprints. Otherwise a lot of other people would be getting convicted in this world for no reason.

- anon63250
22
actually DNA is not contained in hemolymph or red blood cells because they do not have a nucleus. the massive hemoglobin protein contained within the red blood cell does not allow for a nucleus. You make new red blood cells from the stem cells located in your sternum and pelvis.
- anon60053
21
how can dna help scientists?
- anon56388
20
I would like to know the answer to that previous question about finding a person's rapist based on the sperm ejaculation.
- anon55609
19
yes! DNA can tell you your blood type, because dna is in all your cells -- every single one of them.
- anon54709
18
pooh42: if they have some of Dick's DNA to begin with, then yes.
- anon53202
17
how often is DNA fingerprinting used to solve a crime?
- anon52828
16
can a dna of a person be changed and matched to another person?
- anon51227
15
i think that DNA is extremely interesting. we are actually learning about that in school. and this article really helped. thanks!
- anon51187
14
anon48668 has a good question. :)
- anon50860
12
DNA is quite unique, but i honestly don't know how it was invented. i have a question too! if a girl gets raped and the male ejaculates in her, can they trace the sperm to the rapist?
- anon48668
11
how can we make a simple experiment of a dna finger print?
- anon48442
10
can you change your fingerprints?
- anon47087
9
How does Dna fingerprinting and modern genetics research help historians, palaeontologists and archeologists in their research in connection with genetic science and the study of mankind's past?
- anon35699
8
Can DNA tell if a person is the result of incest? For example: If a man rapes the daughter of his biological sister; i.e., Dick and Jane are brother and sister. Jane has a daughter named Dorothy. Dick rapes Dorothy. Dick, Jane and Dorothy are now dead. Can Dorothy's child (fathered by Dick) have his/her DNA tested to determine inception by incest?
- pooh42
6
How are DNA fingerprinting and DNA sequencing similar?
- anon31525
5
Hi. I just have a couple of questions to ask about dna fingerprinting.

Q1- how is dna fingerprinting is obtained?

Q2- why do suspects have the right to refuse to supply samples for dna fingerprinting?

Q3- what is the danger of compulsory dna fingerprints?

- anon27982
3
A blood test can tell you what blood group you are, but DNA is responsible for determining this in the first place.
- anon19586
2
can dna tell me what blood type i have?
- lesquilin

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Written by Brendan McGuigan
Last Modified: 31 January 2010

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