Cortisone cream is a topical corticosteroid ointment that reduces inflammation to areas where applied. Cortisone cream is often used to topically treat arthritis pain from inflammation of the joints, as well as inflammation of the skin caused by various skin disorders and conditions.

Cortisone cream is available in over-the-counter strength, sold as hydrocortisone. Hydrocortisone is a water-soluble, synthetic steroid sold under various names as a cream to relieve itching and minor skin irritation. It is also a primary ingredient in over-the-counter hemorrhoid medication. In prescription strength, cortisone cream may be prescribed to treat skin conditions that are unresponsive to over-the-counter cortisone cream.

Cortisone cream may be prescribed for other reasons not related to skin conditions, as determined by a doctor. Treating a condition with over-the-counter cortisone cream should only be done under the advise of a doctor or pharmacist unless you have successfully treated similar conditions with hydrocortisone before. People who develop a condition, such as rash, itching, or other skin irritation that does not improve within 7 days should consult their family doctor or dermatologist before continuing to apply cortisone cream.

Common uses of cortisone cream include treatment of eczema, psoriasis, dandruff, diaper rash, itching and rash from poison ivy, oak, or sumac, insect bites, and other common skin conditions. Cortisone cream may cause further skin irritation in some people and should not be used for long periods of time. Other side effects that may occur with cortisone cream use include thinning of the skin, dryness, and allergic reactions such as hives.

Cortisone cream does not treat bacterial or fungal skin infections. Signs of skin infection, including localized redness, raised bumps, or hives should be checked by a doctor before applying any over-the-counter treatment. Cortisone cream is applied topically and absorbed into the skin, but generally not into the blood stream. Regardless, patients should tell their doctor or pharmacist of any medications they take as well as any history of allergic reaction to corticosteroids before applying cortisone cream.