I'm on a antimetabolite drug called Methotrexate for my rheumatoid arthritis. The drug actually works really well, it provides pain relief and helps a lot with the inflammation. It has some side effects as well, but I guess that's expected with any medication.
The only side-effect that's really bothering me is the fatigue. I am mostly pain-free when I take the drug, but I feel so tired all the time that I can't do most of what I want to do. If I run a few errands or do the laundry, I'm exhausted and need to lay down for some time.
Is anyone else having this side effect with antimetabolites?