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What is a Therapeutic Vaccine?

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  • Written By: N. Madison
  • Edited By: Jenn Walker
  • Last Modified Date: 02 December 2016
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    Conjecture Corporation
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When most people think of vaccines, they think of those that help to prevent illness. There is, however, another type of vaccine. A person may also receive a therapeutic vaccine, which is given after a person has already contracted an illness. In such a case, the vaccine is typically used to lessen the severity of or treat a condition that has already developed. Therapeutic vaccines are used less often than preventative vaccines because scientists are still studying them.

Preventative vaccines work in a predictable manner. They are usually created to prevent a particular type of infection. In such a case, the agents used to make the vaccine help provoke the response of the patient’s immune system enough to create antibodies against the infection. As a result, the patient is less likely to contract the infection if the body is exposed to it at a later date. This differs from the use of a therapeutic vaccine, which does not prevent the infection at all; instead, it works to treat the infection or reduce the patient's suffering.

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One type of therapeutic vaccine, called sipuleucel T, is designed for use in patients who have prostate cancer. It is intended to help people who have already been diagnosed with this type of cancer. When this prostate cancer vaccine is administered, it is supposed to boost the immune system so it can fight the cancer cells that have already developed. This therapeutic vaccine cannot stop prostate cancer from developing, however.

One of the factors involved in the production of therapeutic vaccines is the manner in which the immune system responds to some types of invaders. In some cases, the immune system’s response is too weak, and sometimes it doesn’t seem to recognize an invasion at all. Therapeutic vaccines may help to stimulate the immune system to fight the invader or destroy cancerous cells.

The development of therapeutic vaccines is in its early stages in comparison to the development of vaccines that prevent illness. To understand this type of vaccine better, scientists conduct experiments to evaluate the feasibility of creating therapeutic vaccines to treat various types of illnesses. For example, some researchers spend time working on the development of therapeutic vaccines for human immunodeficiency virus (HIV), herpes, and other types of cancer. Some research studies have produced promising results, and the use of therapeutic vaccines may someday become as common as the administering of preventative vaccines.

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discographer
Post 3

The fact that vaccines can be used to keep cancer from worsening is very promising. I wish the same sort of thing could be done for chronic illnesses that tend to worsen over time such as diabetes or high blood pressure.

Of course, diseases and cancer are more important and scientists should concentrate on treating these first. Cancer is on the rise and every family has at least one member suffering from one type of cancer or another. Cancer is partly genetic and partly due to environmental factors. If we don't find a treatment for cancer soon, it's going to be the "epidemic" of the 21st century. In a way, it is already.

ysmina
Post 2

@candyquilt-- As far as I know, there are both pre-exposure and post-exposure vaccines for rabies. I recently got post-exposure ones after a stray dog attacked me. But they also have preventative vaccines that people can get before any kind of exposure. I suppose the vaccines I received are considered therapeutic as they help treat and keep the illness from worsening if I do indeed have the virus. On the other hand, if I don't have the virus, then the vaccine is actually working like a preventative one.

candyquilt
Post 1

Is the rabies vaccine a preventative one or a therapeutic one? People don't get it until after they've been bitten by something right?

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