Only the number of neutrons or electrons can vary in an element without changing the actual element.
Ions have a positive or negative electric charge because of an absence or abundance of electrons, not protons. Isotopes on the other hand are still neutral, but they are less stable than the abundant form of the element because they have extra neutrons. Only in a few rare cases do elements have more protons than neutrons (hydrogen, rare and unstable isotopes).
For example, oxygen can have multiple neutron configurations making them different isotopes, but a oxygen atom will always have 8 protons. Oxygen is also an anion because it has a negative two charge, meaning that it has two more electrons than protons.