A parapharyngeal abscess is a collection of infected, swollen, inflamed tissue deep within the neck. Abscesses provide a space for bacteria to thrive and potentially spread to nearby blood vessels and lymph nodes. In most cases, parapharyngeal abscesses arise as a consequence of a severe tonsil, throat, or respiratory tract infection. Treatment in the form of oral antibiotics is usually enough to cure small abscesses before they cause complications. Large pus-filled cysts may need to be surgically drained to prevent airway obstruction and body-wide infection.

The parapharyngeal space is an empty triangular space that is situated between the pharynx, the carotid artery, the internal jugular vein, and several small neck muscles. Most abscesses in the parapharyngeal space are preceded by bacterial infections of the tonsils or pharynx. Pathogens spread through broken, irritated tissue and form cysts in the area. Many different types of bacteria can cause abscesses to develop, including common streptococcus and staphylococcus strains.

A person of any age can develop a parapharyngeal abscess, though the problem is most commonly seen in children and adolescents. Adults who have weakened immune systems are also at an increased risk. The first symptoms of a parapharyngeal abscess are similar those of common throat infections, including a sore throat, difficulty swallowing, mild fever, and fatigue. A growing abscess can cause noticeable swelling in the neck and significant airway obstruction. If the carotid artery or jugular vein is involved, a person may have a very high fever, mental confusion, and dangerous internal hemorrhaging.

It is important for parents to contact a pediatrician when their child shows possible symptoms of a parapharyngeal abscess. A doctor can inspect the throat and tonsils to look for signs of infection. Computerized tomography scans are useful in visualizing the parapharyngeal space and looking for abnormal swelling. After confirming the diagnosis, blood and mucus samples can be collected to check for the specific bacteria involved.

When a parapharyngeal abscess is detected early, it can usually be treated with a four- to six-week course of oral antibiotics. A doctor may decide to drain a growing abscess using a needle that is either inserted through the mouth or through a small cut made in the front of the neck. If airway constriction is present, a patient may need to be admitted into the hospital so specialists can provide oxygen and surgically open the pharynx. A cyst may need to be excised with a scalpel if it is likely to rupture and spread bacteria to blood vessels.