Foot and hand pain can be experienced independently from each other, or they may be experienced at the same time due to the same conditions or separate conditions. The most common causes of foot and hand pain include arthritis, fibromyalgia, nerve pain, injuries and trauma, and soreness from overuse. Arthritis occurs when the ligaments in a joint begin to degrade, causing painful inflammation and other painful joint issues. Arthritis is common in both the hands and feet as well as other parts of the body. Fibromyalgia is a condition in which a person becomes sensitive to pain and pressure throughout the body, and foot and hand pain are common occurrences in sufferers of fibromyalgia.

As humans age, ligaments begin to wear out in joints. This wearing is called arthritis, and it can be a very painful condition for which there is no cure. When the ligaments wear out, bones are allowed to move in ways they would not normally move, which can lead to nerve aggravation or compression, bone degradation, joint stiffness, soreness, and other types of pain. Foot and hand pain often result from arthritis, since both areas of the body contain numerous joints in which arthritis can develop. Treatment for arthritis usually involves medications such as anti-inflammatory pills or topical ointments, as well as painkillers. Regular exercise and stretching can also help alleviate some of the pain associated with arthritis, though in some very severe cases, surgery may be necessary; joint replacement surgeries are sometimes a response to severe or debilitating arthritis.

Fibromyalgia can cause foot and hand pain, though diagnosing this condition can be difficult because doctors and professionals are not entirely sure what it is or what causes it. It is characterized by widespread pain throughout the body, and it is thought that elevated stress levels are a contributing factor to this condition. Foot and hand pain may be symptoms of fibromyalgia, as can other types of pain or sensitivity to pressure. If someone is diagnosed with fibromyalgia or it is suspected they may be suffering from it, alterations of daily activities are usually necessary to lower stress levels.

Nerve damage can cause foot and hand pain, depending on which nerves have been damaged. When a nerve becomes compressed, it may cause pain in any area of the body that is serviced by that nerve. Foot and hand pain would be caused by compression of more than one nerve, since these areas of the body are serviced by different nerves. Compression of a nerve can occur anywhere along that nerve's length, and many nerves originate or run near the spine. Spinal compression can therefore lead to nerve pain in different parts of the body.