The most common symptoms of a staph throat infection are red rash or extremely red-colored skin at the back of the throat, pus-filled blisters appearing just under the surface of the throat tissue, enlarged lymph nodes in the neck, fever, and soreness or pain when swallowing. A localized staph throat infection will likely be confined to this area and may be surrounded by a circular area of white blood cells and bacteria called an abscess. These abscesses break open or burst and the leaking pus or fluid leaks onto the surrounding skin causing more, newer infections. A localized staph throat infection may enter the blood and spread throughout the entire body causing damage to other tissue and organs. A staph throat infection caused by Staphylococcus bacteria is commonly treated using antibiotics.

Most throat infections and sore throats may actually be viral pharyngitis caused by a cold or flu virus. About 10 to 15% of throat infections are bacterial infections and could be caused by Streptococcus bacteria (strep throat) or Staphylococcus bacteria. A staph throat infection may be accompanied by a fever of at least 102 degrees F (38.9 C) and will cause the lymph nodes in the neck to become tender and swollen. The skin in the back of the throat will have a bright red appearance with several white or yellow pus-filled blisters. Strep throat will manifest similar symptoms but may also appear with a flu or cold which causes fever, body aches, and chills.

The word staph is short for Staphylococcus, a term that identifies more than 30 known types of Staphylococcus bacteria. Most staph throat infections in people are caused by the Staphylococcus aureus (S. aureus) bacteria. This generally harmless bacteria can live and thrive in many areas of a healthy person's skin including skin around the nose, mouth, anus and genitals. When, however, the skin is broken, injured, punctured or otherwise compromised, Staphylococcus bacteria can enter the body through this wound and cause infection. Warm and humid climates may also help the Staphylococcus bacteria spread more easily between people through skin-to-skin contact with an the infected area.

S. aureus is commonly found in hospitals and regularly places hospital staff, surgical patients, patients with skin irritations, those with kidney disease, and insulin-dependent diabetics at risk of infection. This type of bacteria can also contaminate sheets, pillow cases, blankets and other similar objects in a hospital or medical care facility. S. aureus may also spread bacteria to the bloodstream causing arthritis, pockets of infection causing pain and swelling under the skin, heart valve inflammation, meningitis, bone inflammation and pneumonia. Even though Staphylococcus bacteria are able to spread through the air, most staph infections are caused by contact with bodily fluids or open sores already contaminated by the bacteria. To get an accurate diagnosis of staph throat infection and its proper treatment, consult a physician or other health care professional.