What are the Most Common Causes of Muscle Pain and Spasm?

Severe muscle spasms in the hand may make handling a toothbrush difficult.
Muscle pain may be a sign of hypothyroidism.
Injury when lifting a heavy object can cause muscle pain and spasms.
There are many causes of pain and cramps in muscles.
Musculoskeletal injuries commonly cause severe muscle pain and spasm.
Pain and muscle cramps may have more than one cause.
Consuming dairy products that are high in vitamin D and calcium may help prevent muscle spasms and pain.
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  • Written By: Vanessa Harvey
  • Edited By: A. Joseph
  • Last Modified Date: 04 November 2015
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The most common causes of muscle pain and spasm are musculoskeletal injuries and a nutritional deficiency. These broad categories of causes, however, have "sub-causes." Injuries and nutritional deficiencies can be caused by playing sports, an accident, loss of blood flow to the muscle, infection or the presence of a tumor. Pain and cramps in muscles can have more than one cause, so the common and the not-so-common causes should be carefully considered to arrive at a correct diagnosis. The severity and type of discomfort that sufferers are experiencing — such as mild or severe, local or diffuse — also should be considered.

Musculoskeletal injuries, particularly a fractured femur or thigh bone, almost always cause severe muscle pain and spasm. This results from the sometimes violent contraction of muscles, which in turn causes the movement of jagged ends of bone cutting and "stabbing" surrounding soft tissue. Splinting is performed not only to greatly reduce blood loss, but also to stop the pain that can accompany the injury.


Low levels of calcium appears on the list of nutritional deficiencies that could lead to a person of any age experiencing muscle pain and spasms. What many people do not realize about nutritional deficiencies is that low levels of a nutrient are not automatically raised by increasing intake of that nutrient. Problems caused by low levels of calcium might have been brought on by low levels of vitamin D, because sufficient vitamin D is required for proper absorption of calcium. A deficiency of the mineral magnesium can also be the underlying cause of muscle pain and spasm.

Some people believe that aging should be considered a common cause for any kind of problem, disorder or disease of the musculoskeletal system. Although it is true that the mature population tends to experience health problems of this and every other type, muscle pain and spasm do not occur in many mature people. It also should be remembered that what seems like a common cause to one person is not necessarily so for another. For example, people who play sports, suffer from an autoimmune disease, have any kind of infection or tumor or have any other condition that restricts blood flow to the muscle could consider their lifestyle and state of health to be the "cause" of the discomfort.


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