Painkiller medications are formally called analgesics. Pain is relieved either by blocking pain signals to the brain or by interfering with those brain signals. There are both narcotic and non-narcotic options that deal with varying degrees of pain.

A Nonsteroidal Anti-Inflammatory Drug (NSAID) are one type of nonnarcotic painkillers. These drugs offer pain relief while lowering fevers and working against inflammation. They are called nonsteroidal to differentiate them from steroids, the most common form of anti-inflammatory medications. Some types of NSAIDs are aspirin, ibuprofen, and diclofenac.

The major side effect to NSAIDs is that they cause the blood to thin and can therefore affect clotting. Many heart patients take aspirin on a regular basis since it helps the blood move through the heart more efficiently. The very thinning that helps on a daily basis makes for a dangerous situation when it comes to surgery. This means anyone taking aspirin regularly must discontinue their regiment before going into a planned surgery.

The next kind of painkiller is non-narcotic paracetamol based, commonly known as acetaminophen. It is sold under names like Tylenol® and Panadol®. Like NSAIDs, acetaminophen is a painkiller and fever reducer. It does not reduce inflammation, which is the one major difference in symptom relief.

Acetaminophen is inexpensive and good for everyday pain relief. It is considered a safe drug when used according to directions. It does not thin the blood like NSAIDs, but it can cause liver damage when taken improperly. It is often found in other drugs like sinus medication and cold medicines, so those with liver issues should check the labels of all painkillers and other types of medications to be sure to avoid acetaminophen.

Narcotic drugs are the strongest type of painkillers. Opioid drugs are any kind of drug that has effects similar to opium, which means that they directly affect the central nervous system and confuse signals that are sent to the brain. Opioids are often mistakenly called opiates, but opiates are actually made from the alkaloids in opium and are a type of opioid.

There are three divisions of opioids that include natural opiates, semi-synthetics, and synthetics. Natural opiates are made from opium. They include morphine and codeine. They are used primarily in the medical field for post-surgical recovery and in a selective manner since they are highly addictive.

Semi-synthetic opiates include the illegal drug heroin and the prescribed ocycodone. Fully synthetic opioids include pethidine, also known as alodan or demerol, methadone and fentanyl. All of the medically used painkillers are considered safe when used appropriately and under the supervision of medical staff. There are extreme concerns for developing addiction in any of these drugs, so patients will be watched carefully to avoid this whenever possible.