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What Are the Different Types of DNA?

Mutations in the DNA of mitochondria can interrupt ATP synthesis, leading to disease.
During fertilization, the mother gives one of her X chromosomes to the offspring, regardless of its sex, while the father's sperm donates either a X or Y chromosome to determine the sex of the offspring.
There are four major types of DNA.
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  • Written By: Karize Uy
  • Edited By: Lauren Fritsky
  • Last Modified Date: 07 September 2014
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In human genetics, there are four general types of deoxyribonucleic acid (DNA). These are the autosomal, mitochondrial, the X chromosome, and the Y chromosome DNA. All of these types are built and encoded with a "program" that hugely predicts a person's appearance, personality, and intelligence. Only 0.1% of the human genetic structure is programmed differently, making each person unique.

The autosomal DNA makes up the 22 out of the 23 chromosome pairs in a human. The autosomes are the genetic material that humans inherit from their parents, who inherit theirs from their parents, and so on. Each autosome goes through a genetic process that randomly pairs up the autosomes from each parent, called "recombination," after which the newly paired autosomes are passed down to the children. This is why children tend to look like their parents, or even their great-grandparents, because the autosomes are imprinted with all the genetic blueprints from each of the preceding generations. The autosomal DNA is very important in finding out a person's ancestry and parentage, especially for people who question who their parents are.

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Mitochondrial DNA is another type that is contained inside the mitochondria, which are considered the "powerhouses" of the cell. The mitochondria are basically the part that gives the cell its energy, and also contains DNA that separately reproduces its own copy. Unlike autosomes that pass down genes from both parents, the mitochondria follow a maternal line, although a mother also passes down her mitochondrial DNA to her sons. This makes mitochondrial testing less accurate if a person wants to trace her family tree, although it may be more effective to use a maternity test to determine a person's biological mother.

Of all the 23 chromosome pairs that make up a human being, only one pair is allocated to determine the sex of the child. This particular pair is called the allosomal pair, which contains the X and Y chromosome DNA. Females generally have two X chromosomes, while males have one each of the X and Y chromosomes. During fertilization, the mother passes down one of her X chromosomes to her offspring, regardless of its sex. The father's sperm, on the other hand, donates his X chromosome to make another female offspring, while passing down his Y chromosome to a male offspring.

Each of these X and Y chromosomes contains ancestral genetic information like the autosomal DNA, but the former chromosomes are not as accurate. The Y chromosome in particular may provide less genetic information than the X, as it is only passed from father to son. Overall, what is remarkable about all these types of DNA is that their primary structure remains unchanged, even though they are produced by random fragments.

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