When one discovers bed bugs in a hotel, the best option is to obtain a refund and move to a different hotel. Often, this will not be a reasonable solution to the problem, however, because the hotel may refuse to give a refund or because other lodgings may not be available. Another possible solution when dealing with bed bugs in a hotel is to change rooms, as not every room in the hotel may be infested. If one absolutely must stay in a room that is infested, the best solution is to take precautions to minimize biting and protect luggage and clothing from the insects. After dealing with bed bugs in a hotel, one can report the incident, or even file a complaint with the hotel after the stay.

In reputable establishments, bed bugs in a hotel room will almost always result in a full refund or a move to a different room. To secure a refund or room change from a nicer hotel establishment, one can often simply call an employee to the room and point out evidence of the bed bugs. A nice hotel may even have a policy permitting both a room change and a refund in order to ensure customer loyalty. These establishments are not immune to bed bugs, but they are usually professional when coping with complaints about them.

In some cases, one may have to complain loudly and firmly about bed bugs in a hotel room. It is essential to demand a new room and to document all evidence of the bed bugs with photographs if possible. Even if one cannot obtain a refund or a room change, it is a good idea to give employees a chance to deal with the problem directly.

In extremely unlucky situations, it may be necessary to put up with bed bugs for a night until better lodgings can be found. While this is not an ideal situation, one can often minimize the damage done by bed bugs. To keep bugs from biting, one should wear thick, tall socks and long pajamas, covering as much skin as possible to keep from getting bit. Keeping one's hair covered is a good idea as well. Luggage should be kept closed and stored off the floor or, if it is safe, left in the car so that clothes will not become infested with bugs.

Reporting bed bugs in a hotel can help other travelers avoid the problem, and there are many websites devoted to listing hotels with infestations or reported incidences. In many cases, however, calling the hotel's owner or contacting the company directly can yield a refund even if hotel employees have refused one. When bedbugs have been properly documented with photographs, one may have an easier time making a case for a refund. Documenting and reporting incidences may encourage hotels to be proactive in keeping rooms cleaner as well.